NOTCH4 Activation and Transmission of Signal to the Nucleus
REACTOME PATHWAYThe NOTCH4 Activation and Transmission of Signal to the Nucleus pathway (Reactome ID: R-HSA-9013700) involves 7 genes and is affected by 5 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting NOTCH4 Activation and Transmission of Signal to the Nucleus
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Dihydroergocristine | — | 187 |
| 2 | Bisphenol A-Glycidyl Methacrylate | — | 197 |
| 3 | Kaempferols | — | 300 |
| 4 | Progesterone | — | 299 |
| 5 | Hexachlorophene | — | 300 |
About the NOTCH4 Activation and Transmission of Signal to the Nucleus Pathway
The NOTCH4 Activation and Transmission of Signal to the Nucleus pathway is catalogued in Reactome (ID: R-HSA-9013700) and involves 7 genes. In the BiohacksAI corpus, 5 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include ADAM10, APH1A, APH1B, NCSTN, PSEN1.