TLR3-mediated TICAM1-dependent programmed cell death
REACTOME PATHWAYThe TLR3-mediated TICAM1-dependent programmed cell death pathway (Reactome ID: R-HSA-9013957) involves 2 genes and is affected by 9 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting TLR3-mediated TICAM1-dependent programmed cell death
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Budesonide | — | 1,000 |
| 2 | Dibucaine | — | 299 |
| 3 | Dimethylphenylpiperazinium Iodide | — | 33 |
| 4 | Edaravone | — | 298 |
| 5 | Fluocinolone Acetonide | — | 295 |
| 6 | Podophyllotoxin | — | 14 |
| 7 | Sulfadimethoxine | — | 300 |
| 8 | vinblastine sulfate | — | 81 |
| 9 | Vemurafenib | — | 298 |
About the TLR3-mediated TICAM1-dependent programmed cell death Pathway
The TLR3-mediated TICAM1-dependent programmed cell death pathway is catalogued in Reactome (ID: R-HSA-9013957) and involves 2 genes. In the BiohacksAI corpus, 9 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include RIPK3, TLR3.