FOXO-mediated transcription of cell death genes
REACTOME PATHWAYThe FOXO-mediated transcription of cell death genes pathway (Reactome ID: R-HSA-9614657) involves 4 genes and is affected by 10 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting FOXO-mediated transcription of cell death genes
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Papaverine | — | 299 |
| 2 | Colchicine | — | 300 |
| 3 | Etazolate | — | 66 |
| 4 | Nocodazole Nocodazole is | — | 215 |
| 5 | plumbagin [Supplementary Concept] | — | 300 |
| 6 | egcg | — | 300 |
| 7 | 11-hydroxypalmatine [Supplementary Concept] | — | 238 |
| 8 | Resveratrol | — | 298 |
| 9 | ly294002 | — | 11 |
| 10 | Anisomycin | — | 247 |
About the FOXO-mediated transcription of cell death genes Pathway
The FOXO-mediated transcription of cell death genes pathway is catalogued in Reactome (ID: R-HSA-9614657) and involves 4 genes. In the BiohacksAI corpus, 10 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include BCL2L11, CREBBP, EP300, FOXO3.