Regulation of FOXO transcriptional activity by acetylation
REACTOME PATHWAYThe Regulation of FOXO transcriptional activity by acetylation pathway (Reactome ID: R-HSA-9617629) involves 6 genes and is affected by 11 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Regulation of FOXO transcriptional activity by acetylation
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | plumbagin [Supplementary Concept] | — | 300 |
| 2 | egcg | — | 300 |
| 3 | Resveratrol | — | 298 |
| 4 | Suramin | — | 300 |
| 5 | Papaverine | — | 299 |
| 6 | Colchicine | — | 300 |
| 7 | Etazolate | — | 66 |
| 8 | Nocodazole Nocodazole is | — | 215 |
| 9 | 11-hydroxypalmatine [Supplementary Concept] | — | 238 |
| 10 | np1 | — | 81 |
| 11 | ly294002 | — | 11 |
About the Regulation of FOXO transcriptional activity by acetylation Pathway
The Regulation of FOXO transcriptional activity by acetylation pathway is catalogued in Reactome (ID: R-HSA-9617629) and involves 6 genes. In the BiohacksAI corpus, 11 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CREBBP, EP300, FOXO3, KAT2B, SIRT1.