Activation of RAC1 downstream of NMDARs
REACTOME PATHWAYThe Activation of RAC1 downstream of NMDARs pathway (Reactome ID: R-HSA-9619229) involves 3 genes and is affected by 4 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Activation of RAC1 downstream of NMDARs
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | sp600125 | — | 117 |
| 2 | Axitinib | — | 298 |
| 3 | Crizotinib | — | 298 |
| 4 | pictilisib | — | 25 |
About the Activation of RAC1 downstream of NMDARs Pathway
The Activation of RAC1 downstream of NMDARs pathway is catalogued in Reactome (ID: R-HSA-9619229) and involves 3 genes. In the BiohacksAI corpus, 4 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CAMK1, CAMKK1, CAMKK2.