RAS processing
REACTOME PATHWAYThe RAS processing pathway (Reactome ID: R-HSA-9648002) involves 6 genes and is affected by 14 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting RAS processing
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Gliotoxin | — | 300 |
| 2 | Lovastatin | — | 300 |
| 3 | paxilline | — | 42 |
| 4 | Tannins Polyphenolic compounds with molecular weights of around 500-3000 daltons and containing enough hydroxyl groups (1-2 per 100 MW) for effective cross linking of other compounds (ASTRINGENTS). | — | 300 |
| 5 | Anthralin | — | 299 |
| 6 | Aurintricarboxylic Acid | — | 184 |
| 7 | Domperidone | — | 299 |
| 8 | Metergoline | — | 144 |
| 9 | Masoprocol | — | 300 |
| 10 | Oxytetracycline | — | 300 |
| 11 | Tetracycline | — | 300 |
| 12 | vinblastine sulfate | — | 81 |
| 13 | Simvastatin | — | 1,000 |
| 14 | palmostatin b | — | 2 |
About the RAS processing Pathway
The RAS processing pathway is catalogued in Reactome (ID: R-HSA-9648002) and involves 6 genes. In the BiohacksAI corpus, 14 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include BCL2L1, CHURC1-FNTB, FNTA, FNTB, ICMT.