A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils.
Nordihydroguaiaretic Acid has been studied across 18 research domains including 🔬 Oncology, 🔬 Inflammation, 🔥 Metabolic, ⚡ Energy & Fatigue, 🫁 Liver & Detox. The primary research focus is 🔬 Oncology with 31% of studies addressing this area.
The following compounds share molecular targets with Nordihydroguaiaretic Acid, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.
This evidence profile for Nordihydroguaiaretic Acid is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.