SHOC2 M1731 mutant abolishes MRAS complex function
REACTOME PATHWAYThe SHOC2 M1731 mutant abolishes MRAS complex function pathway (Reactome ID: R-HSA-9726840) involves 5 genes and is affected by 6 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting SHOC2 M1731 mutant abolishes MRAS complex function
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Sorafenib | — | 300 |
| 2 | Vemurafenib | — | 298 |
| 3 | Dasatinib | — | 299 |
| 4 | Quercetin | — | 300 |
| 5 | myricetin-3-O-galactopyranoside [Supplementary Concept] | — | 300 |
| 6 | Okadaic Acid | — | 300 |
About the SHOC2 M1731 mutant abolishes MRAS complex function Pathway
The SHOC2 M1731 mutant abolishes MRAS complex function pathway is catalogued in Reactome (ID: R-HSA-9726840) and involves 5 genes. In the BiohacksAI corpus, 6 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include ARAF, BRAF, PPP1CC, RAF1, YWHAB.