Drug-mediated inhibition of MET activation
REACTOME PATHWAYThe Drug-mediated inhibition of MET activation pathway (Reactome ID: R-HSA-9734091) involves 1 genes and is affected by 8 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Drug-mediated inhibition of MET activation
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Crizotinib | — | 298 |
| 2 | Afatinib | — | 297 |
| 3 | egcg | — | 300 |
| 4 | Axitinib | — | 298 |
| 5 | Sorafenib | — | 300 |
| 6 | Quercetin | — | 300 |
| 7 | Adenosine Triphosphate | — | 300 |
| 8 | sp600125 | — | 117 |
About the Drug-mediated inhibition of MET activation Pathway
The Drug-mediated inhibition of MET activation pathway is catalogued in Reactome (ID: R-HSA-9734091) and involves 1 genes. In the BiohacksAI corpus, 8 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include MET.