Maturation of TCA enzymes and regulation of TCA cycle
REACTOME PATHWAYThe Maturation of TCA enzymes and regulation of TCA cycle pathway (Reactome ID: R-HSA-9854311) involves 2 genes and is affected by 8 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Maturation of TCA enzymes and regulation of TCA cycle
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Demeclocycline | — | 5 |
| 2 | Dinitrochlorobenzene | — | 300 |
| 3 | kenpaullone | — | 8 |
| 4 | Vorinostat | — | 299 |
| 5 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | — | 150 |
| 6 | Disulfiram | — | 297 |
| 7 | Vanillic Acid | — | 300 |
| 8 | Suramin | — | 300 |
About the Maturation of TCA enzymes and regulation of TCA cycle Pathway
The Maturation of TCA enzymes and regulation of TCA cycle pathway is catalogued in Reactome (ID: R-HSA-9854311) and involves 2 genes. In the BiohacksAI corpus, 8 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include FXN, SIRT3.