Maturation of DENV proteins
REACTOME PATHWAYThe Maturation of DENV proteins pathway (Reactome ID: R-HSA-9918432) involves 7 genes and is affected by 13 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Maturation of DENV proteins
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Hexachlorophene | — | 300 |
| 2 | juglone hydroxylase [Supplementary Concept] catalyzes | — | 279 |
| 3 | Cefdinir | — | 298 |
| 4 | Cefixime | — | 300 |
| 5 | Oxytetracycline | — | 300 |
| 6 | Adenosine Diphosphate Adenosine 5'-(trihydrogen diphosphate). | — | 300 |
| 7 | Ergosterol | — | 300 |
| 8 | plumbagin [Supplementary Concept] | — | 300 |
| 9 | oridonin | — | 300 |
| 10 | Chlorhexidine | — | 299 |
| 11 | Reserpine | — | 297 |
| 12 | Equilin | — | 216 |
| 13 | Calcifediol | — | 300 |
About the Maturation of DENV proteins Pathway
The Maturation of DENV proteins pathway is catalogued in Reactome (ID: R-HSA-9918432) and involves 7 genes. In the BiohacksAI corpus, 13 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include HSPA5, KPNB1, P4HB, PDIA3, SCAP.