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Calcifediol

The major circulating metabolite of VITAMIN D3. It is produced in the LIVER and is the best indicator of the body's vitamin D stores. It is effective in the treatment of RICKETS and OSTEOMALACIA, both in azotemic and non-azotemic patients. Calcifediol also has mineralizing properties.

300+ PubMed studies analyzed · 52 RCTs · Evidence Score: 55

Research Domains

Calcifediol has been studied across 18 research domains including 🦴 Bone & Joint, 🧬 Hormones, 🫘 Kidney, 🔥 Metabolic, 🔬 Inflammation. The primary research focus is 🦴 Bone & Joint with 82% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Calcifediol, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Cholecalciferol
3 shared targets
t091317
2 shared targets
Decitabine
2 shared targets
iodoform
2 shared targets
Feprazone
2 shared targets
Sulfinpyrazone
2 shared targets
Carbaryl
2 shared targets
Calcitriol
3 shared targets
Gliotoxin
2 shared targets
Idazoxan
3 shared targets
Loading evidence profile...

This evidence profile for Calcifediol is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.