Heme assimilation
REACTOME PATHWAYThe Heme assimilation pathway (Reactome ID: R-HSA-9927020) involves 3 genes and is affected by 6 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Heme assimilation
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | diallyl trisulfide | — | 246 |
| 2 | Azathioprine | — | 300 |
| 3 | Azacitidine | — | 298 |
| 4 | Azacitidine | — | 300 |
| 5 | Camptothecin | — | 300 |
| 6 | Vitamin K 3 | — | 300 |
About the Heme assimilation Pathway
The Heme assimilation pathway is catalogued in Reactome (ID: R-HSA-9927020) and involves 3 genes. In the BiohacksAI corpus, 6 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include HBA1, HBA2, HBB.