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Camptothecin

An alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA TOPOISOMERASES, TYPE I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.

300+ PubMed studies analyzed · Evidence Score: 37.7

Research Domains

Camptothecin has been studied across 12 research domains including 🔬 Oncology, 🫁 Liver & Detox, 🧠 Focus & Attention, ⚡ Energy & Fatigue, 🔥 Metabolic. The primary research focus is 🔬 Oncology with 57% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Camptothecin, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Daunorubicin
34 shared targets
Tripterygium
19 shared targets
trichostatic
21 shared targets
Thapsigargin
14 shared targets
Valproic
15 shared targets
cycloheximide
21 shared targets
Emetine
18 shared targets
Azacitidine
17 shared targets
Azacitidine
17 shared targets
Topotecan
14 shared targets
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This evidence profile for Camptothecin is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.