Question 1

What compounds affect the Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters pathway?

Accepted Answer

10 compounds in the BiohacksAI corpus have documented interactions with genes in the Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters pathway (Reactome ID: R-HSA-9931512). These compounds target 2 genes within this pathway.

Question 2

What genes are in the Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters pathway?

Accepted Answer

The Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters pathway involves 2 genes. Key genes include: CREBBP, KMT2A.

#	Compound	Targets Hit	Studies
1	s adenosylhomocysteine	—	300
2	Tannins Polyphenolic compounds with molecular weights of around 500-3000 daltons and containing enough hydroxyl groups (1-2 per 100 MW) for effective cross linking of other compounds (ASTRINGENTS).	—	300
3	Aurintricarboxylic Acid	—	184
4	Nitroblue Tetrazolium Colorless to yellow dye that is reducible to blue or black formazan crystals by certain cells; formerly used to distinguish between nonbacterial and bacterial diseases,	—	300
5	scutellarein	—	113
6	Suramin	—	300
7	Papaverine	—	299
8	Colchicine	—	300
9	Etazolate	—	66
10	Nocodazole Nocodazole is	—	215

BiohacksAI

Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters

Genes in this Pathway

Compounds Affecting Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters

About the Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters Pathway