SLC-mediated transport of amino acids
REACTOME PATHWAYThe SLC-mediated transport of amino acids pathway (Reactome ID: R-HSA-9958863) involves 7 genes and is affected by 11 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting SLC-mediated transport of amino acids
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Aspartic Acid | — | 300 |
| 2 | Glutamic Acid | — | 297 |
| 3 | Glutamic Acid | — | 300 |
| 4 | gamma-Aminobutyric Acid | — | 300 |
| 5 | D-Aspartic Acid | — | 29 |
| 6 | Arginine | — | 300 |
| 7 | Arginine | — | 300 |
| 8 | Lysine | — | 299 |
| 9 | Taurine | — | 300 |
| 10 | Tiagabine | — | 298 |
| 11 | Loratadine | — | 296 |
About the SLC-mediated transport of amino acids Pathway
The SLC-mediated transport of amino acids pathway is catalogued in Reactome (ID: R-HSA-9958863) and involves 7 genes. In the BiohacksAI corpus, 11 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include SLC1A1, SLC1A2, SLC1A3, SLC6A12, SLC6A15.