AKR1B1
MOLECULAR TARGETaldo-keto reductase family 1 member B1
AKR1B1 (aldo-keto reductase family 1 member B1) is targeted by 14 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting AKR1B1
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Quercetin | 2.71 | 14 |
| 2 | Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as | 1.61 | 4 |
| 3 | Chlorogenic Acid | 1.39 | 3 |
| 4 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | 1.39 | 3 |
| 5 | chrysin | 1.10 | 2 |
| 6 | Kaempferols | 1.10 | 2 |
| 7 | Rosmarinic Acid | 1.10 | 2 |
| 8 | Apigenin 5,7,4'-trihydroxy-flavone, | 0.69 | 1 |
| 9 | butein | 0.69 | 1 |
| 10 | Glyceraldehyde | 0.69 | 1 |
| 11 | Indomethacin | 0.69 | 1 |
| 12 | Sulindac | 0.69 | 1 |
| 13 | Tolmetin | 0.69 | 1 |
| 14 | Pennisetum | 0.69 | 1 |
About AKR1B1 as a Drug Target
AKR1B1 (aldo-keto reductase family 1 member B1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 14 compounds with documented AKR1B1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
AKR1B1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.