BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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Indomethacin

A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.

297+ PubMed studies analyzed · 15 RCTs · Evidence Score: 42.3

Research Domains

Indomethacin has been studied across 16 research domains including 🔬 Inflammation, 🦴 Bone & Joint, 😴 Sleep, 🫘 Kidney, 💊 Pain. The primary research focus is 🔬 Inflammation with 24% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Indomethacin, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Tolmetin
6 shared targets
sulindac
8 shared targets
Naproxen
7 shared targets
ns398
6 shared targets
Meloxicam
6 shared targets
butein
5 shared targets
Tigecycline
4 shared targets
Dinoprostone
7 shared targets
Lamivudine
4 shared targets
trolox
4 shared targets
Loading evidence profile...

This evidence profile for Indomethacin is generated deterministically from 297 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.