What compounds target ALOX15?

BiohacksAI has identified 26 compounds that interact with ALOX15 (arachidonate 15-lipoxygenase). Top compounds include: Masoprocol, fisetin, Luteolin 5,7,3',4'-tetrahydroxy-flavone,, Quercetin, Arachidonic Acid. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is ALOX15 (arachidonate 15-lipoxygenase)?

ALOX15 is arachidonate 15-lipoxygenase. It is a molecular target for 26 compounds documented in PubMed bioassay data. UniProt ID: AAC52118. NCBI Gene ID: 246.

ALOX15

MOLECULAR TARGET

arachidonate 15-lipoxygenase

UniProt: AAC52118 NCBI Gene: 24626 compounds

ALOX15 (arachidonate 15-lipoxygenase) is targeted by 26 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting ALOX15

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	Masoprocol	2.40	10
2	fisetin	1.61	4
3	Luteolin 5,7,3',4'-tetrahydroxy-flavone,	1.39	3
4	Quercetin	1.39	3
5	Arachidonic Acid	1.10	2
6	myricetin-3-O-galactopyranoside [Supplementary Concept]	1.10	2
7	Aurintricarboxylic Acid	1.10	2
8	Dipyrone	1.10	2
9	Apigenin 5,7,4'-trihydroxy-flavone,	0.69	1
10	Catechin	0.69	1
11	alpha-Linolenic Acid	0.69	1
12	brl 50481	0.69	1
13	Celecoxib	0.69	1
14	Cholecalciferol Derivative of 7-dehydroxycholesterol formed by ULTRAVIOLET RAYS breaking of	0.69	1
15	Dactinomycin	0.69	1
16	dihydroxyflavone	0.69	1
17	Dihydroxyphenylalanine	0.69	1
18	Ethidium	0.69	1
19	ethopropazine hydrochloride	0.69	1
20	Ethoxyquin Antioxidant; also	0.69	1
21	Hexachlorophene	0.69	1
22	Iodoacetamide	0.69	1
23	juglone hydroxylase [Supplementary Concept] catalyzes	0.69	1
24	Linoleic Acid	0.69	1
25	Procarbazine	0.69	1
26	Pseudoephedrine	0.69	1

About ALOX15 as a Drug Target

ALOX15 (arachidonate 15-lipoxygenase) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 26 compounds with documented ALOX15 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

ALOX15 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.