CDK5
MOLECULAR TARGETcyclin dependent kinase 5
CDK5 (cyclin dependent kinase 5) is targeted by 12 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting CDK5
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | kenpaullone | 2.30 | 9 |
| 2 | alsterpaullone | 2.20 | 8 |
| 3 | indirubin | 2.08 | 7 |
| 4 | Harmine Alkaloid isolated from seeds of PEGANUM HARMALA; ZYGOPHYLLACEAE. It is identical to banisterine, or telepathine, from Banisteria caapi and is | 1.39 | 3 |
| 5 | Apigenin 5,7,4'-trihydroxy-flavone, | 1.10 | 2 |
| 6 | chrysin | 1.10 | 2 |
| 7 | fisetin | 1.10 | 2 |
| 8 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | 1.10 | 2 |
| 9 | hydroxyfasudil [Supplementary Concept] | 1.10 | 2 |
| 10 | Sorafenib | 1.10 | 2 |
| 11 | egcg | 0.69 | 1 |
| 12 | sp600125 | 0.69 | 1 |
About CDK5 as a Drug Target
CDK5 (cyclin dependent kinase 5) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 12 compounds with documented CDK5 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
CDK5 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.