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Ha1077

an active metabolite of fasudil hydrochloride, relaxes the rabbit basilar artery by disinhibition of myosin light chain phosphatase Heading Mapped to: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine / analogs and derivatives

11+ PubMed studies analyzed · Evidence Score: 27.6

Research Domains

Ha1077 has been studied across 12 research domains including 🦴 Bone & Joint, 🔬 Oncology, ❤️ Cardiovascular, 🔥 Metabolic, 🔬 Inflammation. The primary research focus is 🦴 Bone & Joint with 36% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Ha1077, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

fasudil
18 shared targets
uprosertib
14 shared targets
capivasertib
14 shared targets
gsk
21 shared targets
pf
22 shared targets
ruboxistaurin
25 shared targets
y
12 shared targets
afuresertib
9 shared targets
enzastaurin
17 shared targets
k
18 shared targets
Loading evidence profile...

This evidence profile for Ha1077 is generated deterministically from 11 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.