COPS5
MOLECULAR TARGETCOP9 signalosome subunit 5
COPS5 (COP9 signalosome subunit 5) is targeted by 9 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting COPS5
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | shikonin | 4.11 | 60 |
| 2 | naphthazalin | 2.71 | 14 |
| 3 | acetylshikonin | 2.48 | 11 |
| 4 | alkannin | 2.48 | 11 |
| 5 | isobutylshikonin | 2.08 | 7 |
| 6 | DEAD-box RNA Helicases | 0.69 | 1 |
| 7 | Thioctic Acid | 0.69 | 1 |
| 8 | Sphingosine | 0.69 | 1 |
| 9 | Thioctic Acid | 0.69 | 1 |
About COPS5 as a Drug Target
COPS5 (COP9 signalosome subunit 5) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 9 compounds with documented COPS5 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
COPS5 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.