DDIT3
MOLECULAR TARGETDNA-damage inducible transcript 3
DDIT3 (DNA-damage inducible transcript 3) is targeted by 13 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting DDIT3
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Calcimycin | 1.39 | 3 |
| 2 | Fluspirilene | 1.10 | 2 |
| 3 | Ursolic Acid | 0.69 | 1 |
| 4 | cinoxacin | 0.69 | 1 |
| 5 | Clotrimazole | 0.69 | 1 |
| 6 | dihydrorotenone | 0.69 | 1 |
| 7 | Felbamate | 0.69 | 1 |
| 8 | Hexachlorophene | 0.69 | 1 |
| 9 | Mestranol | 0.69 | 1 |
| 10 | paxilline | 0.69 | 1 |
| 11 | streptonigrin | 0.69 | 1 |
| 12 | Tripterygium | 0.69 | 1 |
| 13 | Vigabatrin | 0.69 | 1 |
About DDIT3 as a Drug Target
DDIT3 (DNA-damage inducible transcript 3) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 13 compounds with documented DDIT3 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
DDIT3 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.