FEN1
MOLECULAR TARGETflap structure-specific endonuclease 1
FEN1 (flap structure-specific endonuclease 1) is targeted by 22 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting FEN1
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | myricetin-3-O-galactopyranoside [Supplementary Concept] | 2.08 | 7 |
| 2 | Quercetin | 1.39 | 3 |
| 3 | Aurintricarboxylic Acid | 1.39 | 3 |
| 4 | Norepinephrine Precursor of epinephrine that is secreted by | 1.39 | 3 |
| 5 | Dequalinium | 1.10 | 2 |
| 6 | Diiodotyrosine | 1.10 | 2 |
| 7 | Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as | 1.10 | 2 |
| 8 | Epinephrine | 1.10 | 2 |
| 9 | Ethidium | 1.10 | 2 |
| 10 | Idarubicin | 1.10 | 2 |
| 11 | Levodopa | 1.10 | 2 |
| 12 | Methyldopa | 1.10 | 2 |
| 13 | piceatannol | 1.10 | 2 |
| 14 | Doxycycline | 0.69 | 1 |
| 15 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | 0.69 | 1 |
| 16 | Methylene Blue | 0.69 | 1 |
| 17 | Carmine Coloring matter from | 0.69 | 1 |
| 18 | Cisplatin | 0.69 | 1 |
| 19 | Demeclocycline | 0.69 | 1 |
| 20 | Dithiazanine 3-Ethyl-2-(5-(3-ethyl-2-benzothiazolinylidene)-1,3- pentadienyl)benzothiazolium. | 0.69 | 1 |
| 21 | Oxytetracycline | 0.69 | 1 |
| 22 | streptonigrin | 0.69 | 1 |
About FEN1 as a Drug Target
FEN1 (flap structure-specific endonuclease 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 22 compounds with documented FEN1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
FEN1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.