GPR35
MOLECULAR TARGETG protein-coupled receptor 35
GPR35 (G protein-coupled receptor 35) is targeted by 15 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting GPR35
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Niflumic Acid | 1.79 | 5 |
| 2 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | 1.61 | 4 |
| 3 | PQQ Cofactor | 1.61 | 4 |
| 4 | Kynurenic Acid | 1.61 | 4 |
| 5 | PQQ Cofactor | 1.61 | 4 |
| 6 | PQQ Cofactor | 1.61 | 4 |
| 7 | myricetin-3-O-galactopyranoside [Supplementary Concept] | 1.39 | 3 |
| 8 | Quercetin | 1.39 | 3 |
| 9 | Furosemide | 1.39 | 3 |
| 10 | amlexanox | 0.69 | 1 |
| 11 | Aprepitant | 0.69 | 1 |
| 12 | Bumetanide | 0.69 | 1 |
| 13 | Emetine | 0.69 | 1 |
| 14 | Firefly Luciferin | 0.69 | 1 |
| 15 | Perphenazine | 0.69 | 1 |
About GPR35 as a Drug Target
GPR35 (G protein-coupled receptor 35) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 15 compounds with documented GPR35 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
GPR35 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.