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Emetine

The principal alkaloid of ipecac, from the ground roots of Uragoga (or Cephaelis) ipecacuanha or U. acuminata, of the Rubiaceae. It is used as an amebicide in many different preparations and may cause serious cardiac, hepatic, or renal damage and violent diarrhea and vomiting. Emetine inhibits protein synthesis in EUKARYOTIC CELLS but not PROKARYOTIC CELLS.

298+ PubMed studies analyzed · Evidence Score: 36.9

Research Domains

Emetine has been studied across 18 research domains including 🔬 Oncology, 🏋️ Muscle & Hypertrophy, 🫁 Liver & Detox, ⚡ Energy & Fatigue, 😴 Sleep. The primary research focus is 🔬 Oncology with 10% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Emetine, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Idazoxan
25 shared targets
cycloheximide
32 shared targets
Dactinomycin
26 shared targets
Azacitidine
27 shared targets
Azacitidine
27 shared targets
o-Phthalaldehyde
20 shared targets
Daunorubicin
33 shared targets
Proscillaridin
16 shared targets
Ciclopirox
21 shared targets
Rotenone
24 shared targets
Loading evidence profile...

This evidence profile for Emetine is generated deterministically from 298 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.