GRIN2B
MOLECULAR TARGETglutamate ionotropic receptor NMDA type subunit 2B
GRIN2B (glutamate ionotropic receptor NMDA type subunit 2B) is targeted by 17 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting GRIN2B
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Glutamic Acid | 3.22 | 24 |
| 2 | Glutamic Acid | 3.22 | 24 |
| 3 | Glycine | 2.40 | 10 |
| 4 | eliprodil | 2.40 | 10 |
| 5 | pentamidine | 1.79 | 5 |
| 6 | Dextromethorphan Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of | 1.61 | 4 |
| 7 | Levorphanol | 1.61 | 4 |
| 8 | Aspartic Acid | 1.39 | 3 |
| 9 | cycloserine | 1.39 | 3 |
| 10 | D-Aspartic Acid | 1.10 | 2 |
| 11 | Dextrorphan Dextro form of levorphanol. It acts as | 1.10 | 2 |
| 12 | Ethidium | 1.10 | 2 |
| 13 | Dextrothyroxine | 0.69 | 1 |
| 14 | Dizocilpine Maleate | 0.69 | 1 |
| 15 | Ibotenic Acid | 0.69 | 1 |
| 16 | Memantine AMANTADINE derivative that has some dopaminergic effects. It has been proposed as | 0.69 | 1 |
| 17 | Spermine | 0.69 | 1 |
About GRIN2B as a Drug Target
GRIN2B (glutamate ionotropic receptor NMDA type subunit 2B) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 17 compounds with documented GRIN2B interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
GRIN2B inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.