A biogenic polyamine formed from spermidine. It is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria. It is found as a polycation at all pH values. Spermine is associated with nucleic acids, particularly in viruses, and is thought to stabilize the helical structure.
Spermine has been studied across 18 research domains including 🔬 Oncology, 🫁 Liver & Detox, ⚡ Energy & Fatigue, 🧠 Focus & Attention, 🦴 Bone & Joint. The primary research focus is 🔬 Oncology with 13% of studies addressing this area.
The following compounds share molecular targets with Spermine, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.
This evidence profile for Spermine is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.