IGF1R
MOLECULAR TARGETinsulin like growth factor 1 receptor
IGF1R (insulin like growth factor 1 receptor) is targeted by 25 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting IGF1R
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | foretinib | 4.34 | 76 |
| 2 | tozasertib | 4.33 | 75 |
| 3 | ceritinib | 4.19 | 65 |
| 4 | brigatinib | 3.81 | 44 |
| 5 | nintedanib | 3.61 | 36 |
| 6 | tae 684 | 3.43 | 30 |
| 7 | fedratinib | 3.40 | 29 |
| 8 | entrectinib | 3.18 | 23 |
| 9 | lestaurtinib | 3.04 | 20 |
| 10 | r 406 | 2.83 | 16 |
| 11 | kw 2449 | 2.64 | 13 |
| 12 | linsitinib | 2.64 | 13 |
| 13 | bms 754807 | 2.30 | 9 |
| 14 | asp 3026 | 2.08 | 7 |
| 15 | maleimide | 1.95 | 6 |
| 16 | bastadin 7 | 1.95 | 6 |
| 17 | pf 03814735 | 1.79 | 5 |
| 18 | ilorasertib | 1.79 | 5 |
| 19 | norlichexanthone | 1.79 | 5 |
| 20 | anilinopyrimidine1 | 1.79 | 5 |
| 21 | Crizotinib | 1.10 | 2 |
| 22 | Quercetin | 0.69 | 1 |
| 23 | ly294002 | 0.69 | 1 |
| 24 | Masoprocol | 0.69 | 1 |
| 25 | bdb 3 6 4 1r 4s 5 oxa 2 aza bicyclo 2 2 1 heptan 2 yl piperidin 1 yl 4 methyl 1h ben | 0.69 | 1 |
About IGF1R as a Drug Target
IGF1R (insulin like growth factor 1 receptor) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 25 compounds with documented IGF1R interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
IGF1R inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.