MC1R
MOLECULAR TARGETmelanocortin 1 receptor
MC1R (melanocortin 1 receptor) is targeted by 7 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting MC1R
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | afamelanotide | 4.04 | 56 |
| 2 | intermedine | 3.95 | 51 |
| 3 | alpha-MSH | 3.53 | 33 |
| 4 | melatonan | 3.53 | 33 |
| 5 | bremelanotide [Supplementary Concept] | 2.08 | 7 |
| 6 | setmelanotide | 1.95 | 6 |
| 7 | melanotan-II [Supplementary Concept] synthetic cyclic heptapeptide, | 1.10 | 2 |
About MC1R as a Drug Target
MC1R (melanocortin 1 receptor) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 7 compounds with documented MC1R interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
MC1R inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.