A 13-amino acid peptide derived from proteolytic cleavage of ADRENOCORTICOTROPIC HORMONE, the N-terminal segment of ACTH. ACTH (1-13) is amidated at the C-terminal to form ACTH (1-13)NH2 which in turn is acetylated to form alpha-MSH in the secretory granules. Alpha-MSH stimulates the synthesis and distribution of MELANIN in MELANOCYTES in mammals and MELANOPHORES in lower vertebrates.
Alpha Msh has been studied across 23 research domains including ✨ Skin & Hair, 🔬 Inflammation, 🔬 Oncology, 🛡️ Immunity, 🧠 Focus & Attention. The primary research focus is ✨ Skin & Hair with 63% of studies addressing this area.
The following compounds share molecular targets with Alpha Msh, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.
This evidence profile for Alpha Msh is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.