MIF
MOLECULAR TARGETmacrophage migration inhibitory factor
MIF (macrophage migration inhibitory factor) is targeted by 11 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting MIF
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | ebselen | 4.74 | 113 |
| 2 | e319 | 3.85 | 46 |
| 3 | benzyl isothiocyanate | 3.30 | 26 |
| 4 | allyl isothiocyanate | 3.18 | 23 |
| 5 | phenethylisothiocyanate | 3.18 | 23 |
| 6 | ibudilast | 2.48 | 11 |
| 7 | Hexachlorophene | 1.39 | 3 |
| 8 | Esculin | 1.10 | 2 |
| 9 | Histamine | 1.10 | 2 |
| 10 | Metaraminol | 1.10 | 2 |
| 11 | alyssin [Supplementary Concept] | 0.69 | 1 |
About MIF as a Drug Target
MIF (macrophage migration inhibitory factor) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 11 compounds with documented MIF interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
MIF inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.