MMP14
MOLECULAR TARGETmatrix metallopeptidase 14
MMP14 (matrix metallopeptidase 14) is targeted by 17 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting MMP14
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | epigalocatechin gallate | 5.40 | 220 |
| 2 | clioquinol | 4.03 | 55 |
| 3 | cgs 27023a | 3.76 | 42 |
| 4 | marimastat | 3.47 | 31 |
| 5 | ilomastat | 3.40 | 29 |
| 6 | prinomastat | 2.94 | 18 |
| 7 | chloroxine | 2.71 | 14 |
| 8 | cts 1027 | 2.64 | 13 |
| 9 | batimastat | 2.48 | 11 |
| 10 | tiludronic acid | 2.08 | 7 |
| 11 | ro 319790 | 1.79 | 5 |
| 12 | bdb n 5 adamantan 1 yl 6h 1 3 4 thiadiazin 2 yl 2 benzenesulfonylamino propionamide | 1.10 | 2 |
| 13 | Resveratrol | 0.69 | 1 |
| 14 | Astemizole Antihistamine drug now withdrawn from | 0.69 | 1 |
| 15 | Leflunomide | 0.69 | 1 |
| 16 | Propafenone | 0.69 | 1 |
| 17 | Thioridazine | 0.69 | 1 |
About MMP14 as a Drug Target
MMP14 (matrix metallopeptidase 14) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 17 compounds with documented MMP14 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
MMP14 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.