How many studies have been conducted on Leflunomide?

BiohacksAI has indexed 297 PubMed studies on Leflunomide, including 23 randomized controlled trials (RCTs). 57% of studies involve human subjects.

What are the main research areas for Leflunomide?

The primary research domains for Leflunomide are 🦴 Bone & Joint, 🛡️ Immunity, 🔬 Inflammation. This is based on analysis of 297 PubMed studies using the BiohacksAI evidence platform.

Leflunomide

An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.

297+ PubMed studies analyzed · 23 RCTs · Evidence Score: 51.1

Research Domains

Leflunomide has been studied across 18 research domains including 🦴 Bone & Joint, 🛡️ Immunity, 🔬 Inflammation, 🔬 Oncology, 🫁 Liver & Detox. The primary research focus is 🦴 Bone & Joint with 43% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Leflunomide, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Thiabendazole

17 shared targets

2-Acetylaminofluorene

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This evidence profile for Leflunomide is generated deterministically from 297 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.