NOX4
MOLECULAR TARGETNADPH oxidase 4
NOX4 (NADPH oxidase 4) is targeted by 7 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting NOX4
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | lavendustin c | 2.48 | 11 |
| 2 | diphenyleneiodonium chloride | 2.48 | 11 |
| 3 | Apigenin 5,7,4'-trihydroxy-flavone, | 0.69 | 1 |
| 4 | Kaempferols | 0.69 | 1 |
| 5 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | 0.69 | 1 |
| 6 | Quercetin | 0.69 | 1 |
| 7 | celastrol | 0.69 | 1 |
About NOX4 as a Drug Target
NOX4 (NADPH oxidase 4) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 7 compounds with documented NOX4 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
NOX4 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.