PDE3B
MOLECULAR TARGETphosphodiesterase 3B
PDE3B (phosphodiesterase 3B) is targeted by 11 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting PDE3B
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | milrinone | 4.39 | 80 |
| 2 | isobutylmethylxanthine | 3.71 | 40 |
| 3 | vesnarinone | 2.64 | 13 |
| 4 | pf 04217903 | 2.64 | 13 |
| 5 | cilostamide | 2.56 | 12 |
| 6 | ibudilast | 2.48 | 11 |
| 7 | bw a78u | 1.95 | 6 |
| 8 | Cilostazol | 1.79 | 5 |
| 9 | Papaverine | 1.39 | 3 |
| 10 | Enoximone | 1.10 | 2 |
| 11 | Cyclic GMP Guanosine cyclic 3',5'-(hydrogen phosphate). | 0.69 | 1 |
About PDE3B as a Drug Target
PDE3B (phosphodiesterase 3B) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 11 compounds with documented PDE3B interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
PDE3B inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.