A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed)
Cyclic Gmp has been studied across 21 research domains including 🦴 Bone & Joint, 👁️ Vision & Eye, 🧠 Focus & Attention, 🫘 Kidney, ❤️ Cardiovascular. The primary research focus is 🦴 Bone & Joint with 17% of studies addressing this area.
The following compounds share molecular targets with Cyclic Gmp, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.
This evidence profile for Cyclic Gmp is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.