PTGES
MOLECULAR TARGETprostaglandin E synthase
PTGES (prostaglandin E synthase) is targeted by 18 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting PTGES
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | epigalocatechin gallate | 5.40 | 220 |
| 2 | zileuton | 5.04 | 154 |
| 3 | tilarginine | 4.73 | 112 |
| 4 | ns 398 | 4.28 | 71 |
| 5 | zafirlukast | 3.89 | 48 |
| 6 | embelin | 3.26 | 25 |
| 7 | licofelone | 3.04 | 20 |
| 8 | akba | 2.89 | 17 |
| 9 | 11 keto boswellic acid | 2.83 | 16 |
| 10 | boswellic acid | 2.64 | 13 |
| 11 | atranorin | 2.30 | 9 |
| 12 | Celecoxib | 1.95 | 6 |
| 13 | salvin [Supplementary Concept] | 1.10 | 2 |
| 14 | carnosol | 1.10 | 2 |
| 15 | ns398 | 1.10 | 2 |
| 16 | egcg | 0.69 | 1 |
| 17 | Indomethacin | 0.69 | 1 |
| 18 | bdb chembl3094424 | 0.69 | 1 |
About PTGES as a Drug Target
PTGES (prostaglandin E synthase) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 18 compounds with documented PTGES interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
PTGES inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.