PTPN1
MOLECULAR TARGETprotein tyrosine phosphatase non-receptor type 1
PTPN1 (protein tyrosine phosphatase non-receptor type 1) is targeted by 15 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting PTPN1
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Oleanolic Acid | 4.01 | 54 |
| 2 | Ursolic Acid | 3.58 | 35 |
| 3 | celastrol | 2.56 | 12 |
| 4 | Okadaic Acid | 1.61 | 4 |
| 5 | caffeic acid | 0.69 | 1 |
| 6 | Chlorogenic Acid | 0.69 | 1 |
| 7 | Methylene Blue | 0.69 | 1 |
| 8 | Oleic Acid | 0.69 | 1 |
| 9 | Mepentol [Supplementary Concept] | 0.69 | 1 |
| 10 | Evans Blue | 0.69 | 1 |
| 11 | Lithocholic Acid | 0.69 | 1 |
| 12 | Palmitic Acid | 0.69 | 1 |
| 13 | prunetin | 0.69 | 1 |
| 14 | Suramin | 0.69 | 1 |
| 15 | vanadates | 0.69 | 1 |
About PTPN1 as a Drug Target
PTPN1 (protein tyrosine phosphatase non-receptor type 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 15 compounds with documented PTPN1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
PTPN1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.