PTPN2
MOLECULAR TARGETprotein tyrosine phosphatase non-receptor type 2
PTPN2 (protein tyrosine phosphatase non-receptor type 2) is targeted by 12 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting PTPN2
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | sodium orthovanad | 3.99 | 53 |
| 2 | maslinic acid | 3.89 | 48 |
| 3 | corosolic acid | 3.40 | 29 |
| 4 | isosteviol | 3.26 | 25 |
| 5 | oleanonic acid | 3.14 | 22 |
| 6 | Oleanolic Acid | 2.83 | 16 |
| 7 | 11 keto boswellic acid | 2.83 | 16 |
| 8 | celastrol | 2.08 | 7 |
| 9 | sodium vanadate | 1.95 | 6 |
| 10 | oleanolic acid 3 o succinate | 1.79 | 5 |
| 11 | Ursolic Acid | 1.39 | 3 |
| 12 | Lithocholic Acid | 0.69 | 1 |
About PTPN2 as a Drug Target
PTPN2 (protein tyrosine phosphatase non-receptor type 2) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 12 compounds with documented PTPN2 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
PTPN2 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.