PTPN6
MOLECULAR TARGETprotein tyrosine phosphatase non-receptor type 6
PTPN6 (protein tyrosine phosphatase non-receptor type 6) is targeted by 9 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting PTPN6
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | enoxolone | 4.57 | 96 |
| 2 | sodium orthovanad | 3.99 | 53 |
| 3 | tanshinone iia | 3.74 | 41 |
| 4 | corosolic acid | 3.40 | 29 |
| 5 | dihydrotanshinone i | 2.89 | 17 |
| 6 | tanshinone i | 2.89 | 17 |
| 7 | estramustine phosphate | 2.08 | 7 |
| 8 | celastrol | 0.69 | 1 |
| 9 | Sorafenib | 0.69 | 1 |
About PTPN6 as a Drug Target
PTPN6 (protein tyrosine phosphatase non-receptor type 6) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 9 compounds with documented PTPN6 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
PTPN6 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.