SAE1
MOLECULAR TARGETSUMO1 activating enzyme subunit 1
SAE1 (SUMO1 activating enzyme subunit 1) is targeted by 9 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting SAE1
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | DEAD-box RNA Helicases | 1.10 | 2 |
| 2 | Thioctic Acid | 1.10 | 2 |
| 3 | Thioctic Acid | 1.10 | 2 |
| 4 | Rosmarinic Acid | 0.69 | 1 |
| 5 | Demeclocycline | 0.69 | 1 |
| 6 | Edaravone | 0.69 | 1 |
| 7 | Hexachlorophene | 0.69 | 1 |
| 8 | Methyldopa | 0.69 | 1 |
| 9 | rafoxanide | 0.69 | 1 |
About SAE1 as a Drug Target
SAE1 (SUMO1 activating enzyme subunit 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 9 compounds with documented SAE1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
SAE1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.