What compounds target TACR2?

BiohacksAI has identified 29 compounds that interact with TACR2 (tachykinin receptor 2). Top compounds include: paclitaxel, tamoxifen, saquinavir, indinavir, raloxifene. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is TACR2 (tachykinin receptor 2)?

TACR2 is tachykinin receptor 2. It is a molecular target for 29 compounds documented in PubMed bioassay data. UniProt ID: P21452. NCBI Gene ID: 6865.

TACR2

MOLECULAR TARGET

tachykinin receptor 2

UniProt: P21452 NCBI Gene: 686529 compounds

TACR2 (tachykinin receptor 2) is targeted by 29 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting TACR2

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	paclitaxel	7.17	1301
2	tamoxifen	5.88	358
3	saquinavir	4.98	144
4	indinavir	4.84	125
5	raloxifene	4.77	117
6	alpha naphthoflavone	4.67	106
7	docetaxel	4.63	101
8	terfenadine	4.55	94
9	amiodarone	4.51	90
10	nelfinavir	4.51	90
11	diethylstilbestrol	4.06	57
12	gentian violet	4.03	55
13	fluphenazine	3.91	49
14	ciglitazone	3.81	44
15	Neurokinin	3.33	27
16	bithionol	2.89	17
17	talnetant	2.77	15
18	ebastine	2.64	13
19	sulconazole	2.48	11
20	oxiconazole	2.48	11
21	osanetant	2.48	11
22	benzethonium chloride	2.40	10
23	sb 222200	2.40	10
24	Substance P	2.30	9
25	cetylpyridinium bromide	2.20	8
26	enclomiphene	2.08	7
27	4 nonylphenol	2.08	7
28	Neurokinin B	1.95	6
29	haloprogin	1.95	6

About TACR2 as a Drug Target

TACR2 (tachykinin receptor 2) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 29 compounds with documented TACR2 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

TACR2 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.