BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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Substance P

An eleven-amino acid neurotransmitter that appears in both the central and peripheral nervous systems. It is involved in transmission of PAIN, causes rapid contractions of the gastrointestinal smooth muscle, and modulates inflammatory and immune responses.

299+ PubMed studies analyzed · 8 RCTs · Evidence Score: 44.4

Research Domains

Substance P has been studied across 19 research domains including 💊 Pain, 😴 Sleep, 🔬 Inflammation, 🦴 Bone & Joint, ✨ Skin & Hair. The primary research focus is 💊 Pain with 61% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Substance P, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Neurokinin
4 shared targets
Neurokinin
4 shared targets
osanetant
3 shared targets
Morphine
4 shared targets
talnetant
3 shared targets
Codeine
4 shared targets
Eledoisin
2 shared targets
Kassinin
2 shared targets
sb
2 shared targets
Gabapentin
2 shared targets
Loading evidence profile...

This evidence profile for Substance P is generated deterministically from 299 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.