USP28
MOLECULAR TARGETubiquitin specific peptidase 28
USP28 (ubiquitin specific peptidase 28) is targeted by 10 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting USP28
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | carnosol | 1.10 | 2 |
| 2 | prunetin | 1.10 | 2 |
| 3 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | 0.69 | 1 |
| 4 | Quercetin | 0.69 | 1 |
| 5 | alpha-Linolenic Acid | 0.69 | 1 |
| 6 | salvin [Supplementary Concept] | 0.69 | 1 |
| 7 | celastrol | 0.69 | 1 |
| 8 | piceatannol | 0.69 | 1 |
| 9 | pyrrolnitrin | 0.69 | 1 |
| 10 | withaferin | 0.69 | 1 |
About USP28 as a Drug Target
USP28 (ubiquitin specific peptidase 28) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 10 compounds with documented USP28 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
USP28 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.