Activation of BAD and translocation to mitochondria
REACTOME PATHWAYThe Activation of BAD and translocation to mitochondria pathway (Reactome ID: R-HSA-111447) involves 4 genes and is affected by 5 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Activation of BAD and translocation to mitochondria
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Idarubicin | — | 299 |
| 2 | Masoprocol | — | 300 |
| 3 | egcg | — | 300 |
| 4 | Quercetin | — | 300 |
| 5 | hydroxyfasudil [Supplementary Concept] | — | 11 |
About the Activation of BAD and translocation to mitochondria Pathway
The Activation of BAD and translocation to mitochondria pathway is catalogued in Reactome (ID: R-HSA-111447) and involves 4 genes. In the BiohacksAI corpus, 5 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include AKT3, BAD, YWHAB, YWHAG.