Fertilization
REACTOME PATHWAYThe Fertilization pathway (Reactome ID: R-HSA-1187000) involves 4 genes and is affected by 4 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Fertilization
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Progesterone | — | 299 |
| 2 | Alprostadil | — | 297 |
| 3 | Dinoprostone | — | 296 |
| 4 | Quinidine | — | 298 |
About the Fertilization Pathway
The Fertilization pathway is catalogued in Reactome (ID: R-HSA-1187000) and involves 4 genes. In the BiohacksAI corpus, 4 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CATSPER1, CATSPER2, CATSPER4, KCNU1.