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Quinidine

An optical isomer of quinine, extracted from the bark of the CHINCHONA tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular ACTION POTENTIALS, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.

298+ PubMed studies analyzed · 29 RCTs · Evidence Score: 47.1

Research Domains

Quinidine has been studied across 11 research domains including ❤️ Cardiovascular, 🧠 Focus & Attention, 🫁 Liver & Detox, ⚡ Energy & Fatigue, 🫘 Kidney. The primary research focus is ❤️ Cardiovascular with 33% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Quinidine, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Hydroxyzine
21 shared targets
lidoflazine
21 shared targets
Amitriptyline
24 shared targets
Astemizole
31 shared targets
Dextromethorphan
12 shared targets
Duloxetine
16 shared targets
Nortriptyline
20 shared targets
dilazep
15 shared targets
Promethazine
19 shared targets
Nylidrin
13 shared targets
Loading evidence profile...

This evidence profile for Quinidine is generated deterministically from 298 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.