Classical Kir channels
REACTOME PATHWAYThe Classical Kir channels pathway (Reactome ID: R-HSA-1296053) involves 1 genes and is affected by 5 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Classical Kir channels
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Arachidonic Acid | — | 245 |
| 2 | Spermidine | — | 241 |
| 3 | Putrescine | — | 300 |
| 4 | SCH 23390 [Supplementary Concept] | — | 126 |
| 5 | Spermine | — | 300 |
About the Classical Kir channels Pathway
The Classical Kir channels pathway is catalogued in Reactome (ID: R-HSA-1296053) and involves 1 genes. In the BiohacksAI corpus, 5 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include KCNJ4.