Apoptosis induced DNA fragmentation
REACTOME PATHWAYThe Apoptosis induced DNA fragmentation pathway (Reactome ID: R-HSA-140342) involves 2 genes and is affected by 4 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Apoptosis induced DNA fragmentation
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Methotrexate | — | 289 |
| 2 | Salicylic Acid | — | 298 |
| 3 | Chlorhexidine | — | 299 |
| 4 | Reserpine | — | 297 |
About the Apoptosis induced DNA fragmentation Pathway
The Apoptosis induced DNA fragmentation pathway is catalogued in Reactome (ID: R-HSA-140342) and involves 2 genes. In the BiohacksAI corpus, 4 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include HMGB1, KPNB1.